Distinguishing self from world: understanding the neural basis of schizophrenia

区分自我与世界：了解精神分裂症的神经基础

• 批准号: nhmrc : GNT1090507
• 负责人: A/Pr Thomas Whitford
• 金额: $ 41.18万
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/distinguishing-self-world-basis-schizophrenia/1345804
• 关键词: Distinguishing; self; world; understanding; neural

Self-generated sensations - such as tickling oneself - typically evoke less activity in the EEG than physically identical, externally-produced sensations. Schizophrenia patients do not exhibit this “electrophysiological self-suppression” (ESS), which accounts for their characteristic tendency to misattribute their own thoughts and actions to other people. This project aims to rectify ESS levels in schizophrenia by artificially altering patients’ sensory feedback to self-generated actions.

与身体上相同的外部产生的感觉相比，自我产生的感觉--比如挠自己--通常在脑电中引起的活动较少。精神分裂症患者没有表现出这种“电生理自我抑制”(ESS)，这解释了他们特有的倾向，即将自己的想法和行为错误地归因于他人。这个项目旨在通过人为地将患者的感觉反馈改变为自我产生的动作来纠正精神分裂症患者的ESS水平。