IDENTIFICATION OF PATIENTS WITH FAMILIAL PHEOCHROMOCYTOMA/VON HIPPLE LINDAU SYN

家族性嗜铬细胞瘤/VON HIPPLE LINDAU SYN 患者的识别

• 批准号: 6275834
• 负责人: SALLY CARTY
• 金额: $ 1.91万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6275834
• 关键词: adrenal medulla neoplasm; autosomal dominant trait; brain neoplasms; clinical research; eye neoplasms; family genetics; genetic disorder diagnosis; human subject; neoplasm /cancer diagnosis; nervous system neoplasms; pheochromocytoma

Prospective investigation of families with an apparent excess of pheochromocytoma will allow earlier detection, syndrome delineation and improved outcome. Pheochromocytoma is a neoplasm of the adrenal medulla that is usually benign, sporadic and unilateral, and such cases are not the subject of this protocol. Pheochromocytoma is occasionally one manifestation of inherited autosomal dominant endocrine/neurologic disorders. These include, but are not limited to MEN-IIa, MEN-IIb, von Hippel-Lindau disease )VHL), and neurofibromatosis.

对明显过量的家庭的前瞻性调查 嗜铬细胞瘤将允许更早的检测，综合征描绘， 改善结果。 嗜铬细胞瘤是肾上腺髓质的肿瘤 这通常是良性的，散发性的和单侧的，这样的情况下， 本议定书的主题。 嗜铬细胞瘤偶尔是一种 遗传性常染色体显性内分泌/神经系统表现 紊乱这些包括但不限于MEN-IIa、MEN-IIb、von Hippel-Lindau病（VHL）和神经纤维瘤病。