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STUDIES OF ABNORMAL SEXUAL DIFFERENTIATION AND DEVELOPMENT

STUDIES OF ABNORMAL SEXUAL DIFFERENTIATION AND DEVELOPMENT
异常性别分化和发育的研究
批准号：
6276736
负责人：
PETER A LEE
金额：
$1.51万
依托单位：
CHILDREN'S HOSP PITTSBURGH/UPMC HLTH SYS
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6276736
关键词：
adolescence (12-20) clinical research cryptorchidism developmental genetics gene mutation hormone regulation /control mechanism human puberty human subject infant human (0-1 year) inhibin middle childhood (6-11) molecular pathology reproductive system disorder diagnosis sex development disorder

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中文摘要
翻译
利用分子生物学、激素水平和反应等临床指标 诊断研究，性变态的病理生理学方面 差异化正在被定义。对遗传基因的新强调 男性分化障碍中的突变和抑制素B水平 尤其是婴儿和青春期男性的隐睾症。
英文摘要
Using molecular biology, hormone levels and responses and other clinical diagnostic studies, aspects of pathophysiology of abnormal sexual differentiation are being defined. The new emphasis in upon genetic mutations and inhibin B levels in disorders of male differentiation, particularily cryptorchidism among infants and pubertal aged males.
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会议论文
LUPRON DEPOT IN THE TREATMENT OF CENTRAL PRECOCIOUS PUBERTY
ADOLESCENT MALES W VARICOCELE: IDENTIFICATION OF THOSE AT RISK FOR INFERTILITY
PUBERTAL GONADOTROPIN RESPONSES TO GNRH ANALOGUE (LEUPROLIDE) FOR DIAGN TESTING
OUTCOME STUDIES AMONG ADULTS BORN WITH INCOMPLETE GENITAL DEVELOPMENT
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