ANALYSIS OF HEART RATE VARIABILITY

人体能量代谢的控制涉及一个复杂的网络， 包括自主神经系统的神经和体液信号。 它 很明显，自主神经系统的交感神经分支 在这些控制中发挥重要作用。 肾上腺素和 去甲肾上腺素是评估交感神经系统的常用技术。 活动 副交感神经系统的作用已经很多 更难评估。 我们发明了一种光谱技术 心率变异性分析与心率药物调控 它允许测量进入心脏的自主输入， 反映了身体其他部位的自主活动。 我们研究了 交感神经和副交感神经改变， 重量. 我们现在想检查的影响自主活动的 盐酸芬特明，一种通常用于促进减肥的药物。

The control of energy metabolism in man involves a complex network of neural and humoral signals which include the autonomic nervous system. It is clear that the sympathetic division of the autonomic nervous system has an important role to play in these controls. Measures of epinephrine and norepinephrine are the usual techniques for evaluating sympathetic activity. The role of the parasympathetic nervous system has been much more difficult to evaluate. We have devised a technique of spectral analysis of heart rate variability and drug manipulation of heart rate that permits measures of autonomic input into the heart which we believe reflect autonomic activity elsewhere in the body. We have studied sympathetic and parasympathetic alteration as patients vary in body weight. We now wish to examine the effects on autonomic activity of phentermine hydrochloride, a drug commonly used to promote weight loss.