PHASE RESPONSE CURVE FOR MELATONIN IN ELDERLY PATIENTS

老年患者褪黑激素的相响应曲线

• 批准号: 6278120
• 负责人: ALFRED J LEWY
• 金额: $ 2.86万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6278120
• 关键词: age difference; clinical research; clinical trials; hormone metabolism; hormone therapy; human middle age (35-64); human old age (65+); human subject; human therapy evaluation; human very old age (85+); melatonin; oral administration

This is a double-blind, placebo controlled clinical trial of oral melatonin administration in sighted subjects between the ages of 50 and 90. The specific goals of this project are to characterize the shape of the melatonin phase response curve (PRC) in the elderly and compare the shape of the PRC to that of a younger population in order to determine if it is quantitatively, as well as qualitatively, similar.

这是一项双盲、安慰剂对照的口服 褪黑激素给药于年龄在50岁和50岁之间的有视力的受试者 90. 该项目的具体目标是描述 老年人褪黑激素时相反应曲线（PRC）， 中国的形状，以确定是否年轻人口， 它在数量上和质量上都是相似的。