课题基金 / 基金详情

LEVODOPA PHARMACOKINETICS AND PHARMACODYNAMICS

LEVODOPA PHARMACOKINETICS AND PHARMACODYNAMICS
左旋多巴药代动力学和药效学
批准号：
6278110
负责人：
JOHN G NUTT
金额：
$2.86万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6278110
关键词：
Parkinson's disease antiparkinson drugs blood chemistry clinical research clinical trials dihydroxyphenylalanine drug metabolism drug screening /evaluation human subject human therapy evaluation mental disorder chemotherapy pharmacokinetics

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中文摘要
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英文摘要
This study examines the hypothesis that the fluctuating clinical on-off phenomenon accompanying L-DOPA therapy for Parkinson's disease may be due to alterations in the plasma concentrations of the drug. This protocol will examine this hypothesis by appropriate clinical studies.
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会议论文
METHYLPHENIDATE IN PARKINSON'S DISEASE
Methylphenidate in PD
DBS , Deep Brain Stimulation and Levodopa
Levodopa Pharmacokinetics and Pharmacodynamics