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DDAVP INDUCED HYPONATREMIA FOR TREATMENT OF OLIGOHYDRAMNIOS

DDAVP INDUCED HYPONATREMIA FOR TREATMENT OF OLIGOHYDRAMNIOS
DDAVP 诱导低钠血症治疗低钠血症
批准号:
6278390
负责人:
Michael Glenn Ross
金额:
$3.92万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-12-01 至 1998-11-30

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中文摘要
翻译
尽管羊水过少的严重后果, 增加羊水的临床方法。最近的研究表明 一种新的治疗羊水过少的潜在效用, 母体给予DDAVP以增加胎儿尿流。DDAVP原因 母体和胎儿肾脏排泄量较低, 浓缩尿液由于母亲保留水分, 血浆渗透压降低,胎儿尿流量增加。这 研究将检查母体DDAVP的长期影响。
英文摘要
Despite the significant consequences of oligohydramnios there are few clinical approaches to increase amniotic fluid. Recent studies indicate the potential utility of a novel treatment for oligohydramnios using maternal DDAVP administration to increase fetal urine flow. DDAVP causes the maternal and fetal kidney to excrete a lower volume of more concentrated urine. As the mother retains water, maternal and fetal plasma osmolality is reduced and fetal urine flow is increased. This study will examine the long term effect of maternal DDAVP.
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