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RANDOMIZED, COMPARATIVE TRIAL OF AZT & DDI IN HIV INFECTED OR EXPOSED CHILDREN

RANDOMIZED, COMPARATIVE TRIAL OF AZT & DDI IN HIV INFECTED OR EXPOSED CHILDREN
AZT 的随机比较试验
批准号：
6280825
负责人：
ANN PETRU
金额：
$2.39万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6280825
关键词：
2'3' dideoxyinosine AIDS therapy HIV infections candidiasis clinical research clinical trial phase I human subject human therapy evaluation nervous system disorder pediatric AIDS postnatal growth disorder zidovudine

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中文摘要
翻译
这项研究的目的是观察对出生儿童的早期干预
英文摘要
The aim of this study was to look at early intervention in children born to infected mothers who presented with symptoms suggestive of rapidly progressive disease, including persistent oral dandidiasis, failure to thrive, encephalopathy, or frank AIDS. These children were suspected to have poor longterm prognosis and usually had high viral loads. It was hoped that early intervention with antiretroviral agents may prevent the early and rapid decline of CD4s and immunologic function.
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