MOPPS MULTIPLE OPPORTUNISTIC PATHOGEN PREVENTION STUDY

MOPPS 多种机会性病原体预防研究

• 批准号: 6308639
• 负责人: ANN PETRU
• 金额: $ 2.58万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6308639
• 关键词: atovaquone; azithromycin; chemoprevention; clinical research; clinical trials; combination chemotherapy; human subject; human therapy evaluation; microorganism disease chemotherapy; opportunistic infections; pediatric AIDS; sulfamethoxazole; trimethoprim

There are a number of organisms that can cause trouble for children with HIV and we have a group of drugs which, if used in the right combination, might be useful in preventing some or most of these infections. The study will randomize patients to receive either TMP-SMX or the combination of atovaquone and azithromycin with appropriate placebos.

有许多生物体会给儿童带来麻烦， 我们有一组药物，如果组合正确， 可能有助于预防部分或大部分这些感染。 研究 将随机分配患者接受TMP-SMX或联合治疗 阿托伐醌和阿奇霉素与适当的安慰剂。