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GLYCOXIDATION AND MACROVASCULAR DISEASE IN IDDM

GLYCOXIDATION AND MACROVASCULAR DISEASE IN IDDM
IDDM 中的糖氧化和大血管疾病
批准号：
6280120
负责人：
TIMOTHY J LYONS
金额：
$2.73万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6280120
关键词：
biomarker clinical research collagen diabetic angiopathy disease /disorder proneness /risk human subject insulin dependent diabetes mellitus oxidative stress oxidized lipid pathologic process

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We will aim to identify new markers to identify diabetic patients at particular risk of disease progression. The continued accumulation, in the future, of clinical information on the incidence of MVD in the DCCT/EDIC cohort will enhance the value of our presently proposed characterizations of lipid profiles and glycoxidative damage to lipids and collagen and will increase the power of our analyses. Our study may suggest mechanisms of disease, providing possible rationales for new preventive or interventive strategies.
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