SILASTIC GEL SHEETING IN KELOID & HYPERTROPHIC SCAR TREATMENT

疤痕疙瘩中的硅橡胶凝胶片

• 批准号: 6119932
• 负责人: C HAYCOX
• 金额: $ 0.76万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 1999-09-27
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6119932
• 关键词: bioengineering /biomedical engineering; biomedical resource; health care; human tissue; injury; skin

Keloid and hypertrophic scars are fibrous growths resulting from tissue response to trauma, inflammation, surgery, burns or, occasional spontaneous occurrence. It has been determined that silicone gel is effective in the reduction of scar formation, however the mode of action has not yet been explained. This study involves the analysis of human dermal tissue by electron spectroscopy for chemical analysis (ESCA) after exposure to silastic gel sheeting. The goal is to determine the presence and document the migration of silicone through the dermal tissue.

瘢痕疙瘩和增生性瘢痕是由 组织对创伤、炎症、手术、烧伤或偶尔的反应 自发发生的。已确定硅胶为 在减少疤痕形成方面有效，但模式 行动尚未得到解释。这项研究涉及到分析 用于化学分析的人皮肤组织的电子能谱 (ESCA)暴露于硅橡胶凝胶薄膜后。我们的目标是 通过以下途径确定硅胶的存在并记录其迁移 皮肤组织。