EFFECT OF MATERNAL CALCIUM SUPPLEMENTATION ON INFANT BONE MINERAL CONTENT

怀孕期间的钙需求量显著增加，以满足 母亲和发育中的胎儿的需要。这可能会导致 母亲的骨密度丢失(高达3.8%的脊柱骨密度)。这一损失 可能是饮食中钙摄入量不足的综合结果 怀孕所需的钙，以及增加的尿量 怀孕期间钙的排泄。从我们对的初步研究 怀孕的青少年，前24小时的饮食召回显示 计算的膳食钙摄入量为每天978+/-532毫克，包括 产前补充剂中的钙含量为250毫克/天 低于怀孕的RDA。青春期母亲的分娩是众所周知的 导致单个婴儿的出生体重较低。然而，它是 尚不清楚它是否与骨矿物质状态改变有关。这个 青春期母体缺钙对母体血钙的影响 婴儿BMC还没有被研究过。这项建议的总体目标是 确定当前孕妇膳食钙摄入量的影响， 而孕期补钙，会对婴儿的骨骼产生影响 矿物质含量。

Calcium requirements during pregnancy increase significantly to meet the needs of the mother and the developing fetus. This could result in the maternal loss of bone mineral density (up to 3.8% spinal BMD). This loss of BMD may be the combined result of dietary calcium intake falling short of the calcium requirements for pregnancy, and the increased urinary calcium excretion during pregnancy. From our preliminary study of 64 pregnant adolescents, the dietary recall of the previous 24 hours revealed a calculated dietary calcium intake of 978 +/- 532 mg/day, including the 250 mg/day of calcium present in the prenatal supplementation, which is below the RDA for pregnancy. Births from adolescent mothers are known to result in lower birth weight of the individual infants. However, it is not known whether it is associated with altered bone mineral status. The effect of maternal calcium depletion during adolescent pregnancy on the infant BMC has not been studied. The overall aim of this proposal is to determine the effects that the current maternal dietary calcium intake, and calcium supplementation in pregnancy, will have on the infant bone mineral content.