EFFECTS OF TAR IN HUMANS

吸烟和接触二手烟与吸烟有关， 人类疾病。烟雾中的焦油成分显示出最大的 毒性然而，加热但不燃烧的香烟， 较低的焦油含量。因此，本研究将调查 一种替代的烟草加热香烟。的几项措施 支气管肺泡功能、炎症、肺和心血管 转换前后将评估生理学和诱变剂暴露 并与非吸烟者进行比较。

Tobacco smoking and exposure to second-hand smoke have been implicated in human diseases. The tar components of smoke demonstrate the greatest toxicity. However cigarettes which heat,but do not burn,tobacco deliver lower levels of tar. This study will therefore investigate the impact of an alternative tobacco-heating cigarette. Several measures of bronchoalveolar function, inflammation, pulmonary and cardiovascular physiology and exposure to mutagen will be assessed before and after switch to the alternative cigarette and compared with non-smokers.