EFFECTS OF TAR IN HUMANS

吸烟和接触二手烟被认为与 人类疾病。烟雾中的焦油成分显示出最大的 毒性。然而，加热但不燃烧的香烟，烟草传递 较低的焦油含量。因此，这项研究将调查 一种替代的烟草加热香烟。几项措施 支气管肺泡功能、炎症、肺和心血管 转换前和转换后将评估生理和暴露于诱变剂 并与非吸烟者进行比较。

Tobacco smoking and exposure to second-hand smoke have been implicated in human diseases. The tar components of smoke demonstrate the greatest toxicity. However cigarettes which heat,but do not burn,tobacco deliver lower levels of tar. This study will therefore investigate the impact of an alternative tobacco-heating cigarette. Several measures of bronchoalveolar function, inflammation, pulmonary and cardiovascular physiology and exposure to mutagen will be assessed before and after switch to the alternative cigarette and compared with non-smokers.