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EFFECTS OF SEX STEROIDS ON GROWTH HORMONE CONCENTRATIONS

EFFECTS OF SEX STEROIDS ON GROWTH HORMONE CONCENTRATIONS
性类固醇对生长激素浓度的影响
批准号：
6282592
负责人：
CHARLES SKLAR
金额：
$6.94万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-01-06 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6282592
关键词：
antineoplastics clinical research combination cancer therapy drug adverse effect hormone regulation /control mechanism human puberty human subject leukemia lymphoma neoplasm /cancer chemotherapy neoplasm /cancer radiation therapy pediatric neoplasm /cancer sex hormones somatotropin

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中文摘要
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英文摘要
We will test the hypothesis that the therapies currently employed to treat childhood leukemias and lymphomas (systemic/intrathecal chemotherapy and lwo-dose, 1800cGy, cranial radiation) cause damage to the neuroregulatory centers int he brain responsible for the sex steroid mediated increase in growth hormone production. As a consequence, these individuals produce normal amounts of GH in the prepubertal years but fail to demonstrate the expected increase in GH concentration in response to sex steroids (both endogenous and exogenous).
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EFFECTS OF SEX STEROIDS ON GROWTH HORMONE CONCENTRATIONS FOLLOWING
ORAL GLULCOSE TOLERANCE TESTING IN CHILDREN FOLLOWING FUNDOPLICATION
  • 批准号：
    3904506
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    CHARLES SKLAR
  • 依托单位：
    NEW YORK UNIVERSITY
EFFECTS OF SEX STEROIDS ON GROWTH HORMONE CONCENTRATIONS
ORAL GLULCOSE TOLERANCE TESTING IN CHILDREN FOLLOWING FUNDOPLICATION
  • 批准号：
    3884862
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    CHARLES SKLAR
  • 依托单位：
    NEW YORK UNIVERSITY
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