INFLUENCE OF PREVIOUS INFECTION ON THE HOST DEFENSE EFFECTS OF GRANULOCYTE COLONY
INFLUENCE OF PREVIOUS INFECTION ON THE HOST DEFENSE EFFECTS OF GRANULOCYTE COLONY
批准号:
6289412
负责人:
Peter Q Eichacker
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
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英文摘要
Studies suggest that the production of endogenous anti-inflammatory agents during sepsis reduces host defense and predisposes to subsequent infection. Whether such a state of immunosuppression during sepsis actually exists or is reversible with the administration of proinflammatory agents is unclear. However, use of recombinant granu- locyte colony stimulating factor (G-CSF) to augment host defense following the onset of sepsis in critically ill patients has been proposed. Using a rat model, we plan to determine whether an initial episode of infection and sepsis augments the host defense effects of G- CSF during a subsequent episode.
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Effects of Therapeutic Recombinant Granulocyte Colony Stimulating Factor
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批准号:6227873
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
TYROSINE KINASE INHIBITION IN A CANINE MODEL OF S. AUREUS INFECTION
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批准号:6289408
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
TYPE OF INFECTION ON EFFECTS OF ENDOTOXIN ANALOG
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批准号:6414070
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Influence Of Systemic Inflammation On The Effects Of Rec
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批准号:6546515
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Site,severity& Infection Type Influence On Superoxide Di
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批准号:6825056
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
NF-kappa B in Murine Sepsis
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批准号:7003964
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Influence Of Site, Severity, And Type Of Infection On Ef
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批准号:6993911
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Pretreatment Sublethal B. Anthracis Lethal Toxin in Rats
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批准号:7003993
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Site,severity& Infection Type Influence On Superoxide Di
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批准号:6683812
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
NF-kappa B in Murine Sepsis
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批准号:7215794
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
PA-mAb in a Rat Model of Anthrax Sepsis
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批准号:7215804
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Comparison of Anthrax Edema and Lethal Toxins in a Rat
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批准号:7215821
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
NF-kappa B in Murine Sepsis
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批准号:7332172
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Selective inhibition of p38 mitogen activated protein kinase with the pyridinyl
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批准号:7593092
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项目类别:
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资助金额:$4.44万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Selective inhibition of p38 mitogen activated protein kinase with the pyridinyl
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批准号:7733610
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项目类别:
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资助金额:$5.4万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
EFFECTS OF SK 107647, AN IMMUNOSTIMULATORY AGENT, IN A CANINE MODEL OF GRAM-NEGAT
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批准号:6289413
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
THE INFLUENCE OF SITE AND SEVERITY OF INFECTION
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批准号:6289407
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
THE INFLUENCE OF FLUID ADMINISTRATION ON THE EFFECTS OF TUMOR NECROSIS FACTOR SOL
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批准号:6289420
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
Nitric Oxide Inhibition With DTPA/Fe3--Rat Model Sepsis
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批准号:7212428
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
The Effects of B. anthracis Cell Wall in a Small Animal
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批准号:7332590
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Peter Q Eichacker
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依托单位:
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