EFFECTS OF DENTAL TREATMENT DURING PREGNANCY ON CHILDHOOD DEVELOPMENT

工作总结：去年，我们分析了脐带汞含量的数据，发现一位母亲每周吃的鱼粉数量与她的脐带汞含量之间存在统计学意义上的显著关联。我们还发现，在怀孕期间去除汞合金的数量与脐带汞水平之间存在统计学上显著的关系。在分析这些数据的过程中，我们发现了数据中的一个模式，表明它们在实验室分析中存在问题。样品正在实验室重新分析，一旦测量重复，我们将重新进行分析。虽然其他研究人员已经使用脐带组织作为有机汞的生物监测介质，但这是第一次尝试使用脐带组织来测量怀孕期间接触汞蒸气的情况。当数据可用时，我们将完成关于怀孕期间牙科治疗与脐带汞水平之间关系的论文。今年，我们计划对更大的队列进行分析，以了解怀孕期间牙科治疗对儿童发育的影响。-脐带，汞，汞合金，牙科，鱼类消费，甲基汞，汞蒸气-人类受试者：访谈，问卷调查或仅调查

Summary of Work: Last year, we analyzed the umbilical cord mercury data and found a statistically significant association between the number of fish meals a mother reported eating a week and her umbilical cord mercury level. We also found a statistically significant relationship between the number of amalgams removed during pregnancy and umbilical cord mercury levels. In the process of analyzing these data, we discovered a pattern in the data that suggested their had been a problem in the laboratory analysis. The samples are being reanalyzed in the laboratory and we will re-do our analysis once the measurements are repeated. Although other researchers have used cord tissue as a biologic monitoring medium for organic mercury, this is the first study to try to use it to measure exposure to mercury vapor during pregnancy. When the data are available we will finish the paper on the relationship between dental treatment during pregnancy and cord mercury levels. This year we plan to analyze the larger cohort for the effect of dental treatment during pregnancy on childhood development.. - umbilical cord, mercury, amalgams, dental, fish consumption, methyl mercury, mercury vapor - Human Subjects: Interview, Questionaires, or Surveys Only