Does vitamin D supplementation prevent progression of knee osteoarthritis? A randomised controlled trial
Does vitamin D supplementation prevent progression of knee osteoarthritis? A randomised controlled trial
批准号:
nhmrc : 605501
负责人:
A/Pr Anita Wluka
金额:
$67.8万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2014-12-31
中文摘要
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英文摘要
Observational evidence suggests that vitamin D deficiency may have a role in the causes of osteoarthritis (OA) and there are biologically plausible mechanisms to explain this. There is, however, no evidence which shows that intervening with vitamin D supplementation can slow the progression of OA. This study will compare knee OA structural changes in patients receiving vitamin D supplementation with those receiving a placebo. Use of MRI will provide sensitive measures of knee OA changes.
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