ULTRA LOW DOSE NALTREXONE & HEROIN WITHDRAWAL: PILOT STUDY

超低剂量纳曲酮

• 批准号: 6263940
• 负责人: Ricardo Alberto Cruciani
• 金额: $ 7.95万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6263940
• 关键词: clinical research; detoxification; dosage; drug abuse therapy; drug withdrawal; heroin; human subject; naltrexone

The goal of this study is to determine the potential benefit of the use of ultra-low dose naltrexone to prevent withdrawal symptoms in drug addicts during detoxification from heroin. This protocol is based on animal studies that showed that ultra-low dose naltrexone can prevent opioid withdrawal symptoms after abrupt discontinuation of opioids in chronically treated animals.

本研究的目的是确定使用超低剂量纳曲酮预防吸毒者在海洛因戒毒过程中出现戒断症状的潜在益处。 该方案基于动物研究，该研究表明超低剂量纳曲酮可以预防长期治疗动物突然停用阿片类药物后的阿片类药物戒断症状。