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DELAVIRDINE MESYLATE IN TRIPLE & QUADRUPLE COMBINATIONS IN HIV 1

DELAVIRDINE MESYLATE IN TRIPLE & QUADRUPLE COMBINATIONS IN HIV 1
甲磺酸地拉韦啶三重装
批准号：
6297244
负责人：
Joseph J Eron
金额：
$0.02万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6297244
关键词：
AIDS therapy HIV infections clinical research combination chemotherapy delavirdine drug screening /evaluation human subject human therapy evaluation indinavir lamivudine virus RNA zidovudine

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中文摘要
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英文摘要
The purpose of this study is to compare the safety and tolerance of combination therapies of delavirdine, zidovudine, indinavir, and lamivudine; and to compare the antiviral activity of these combinations as measured by the change from baseline in CD4 cell count and plasma HIV-1 RNA PCR levels, the percent of patients whose plasma HIV-1 RNA PCR level drops below 5000 copies/mL, and the percent of patients whose plasma HIV-1 RNA PCR level falls below the level of detection.
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