CHAVI 001: ACUTE HIV-1 INFECTION PROSPECTIVE COHORT STUDY

CHAVI 001：急性 HIV-1 感染前瞻性队列研究

• 批准号: 7716860
• 负责人: Joseph J Eron
• 金额: $ 10.44万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-02 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7716860
• 关键词: Acute; Affect; Chronic; Cohort Studies; Computer Retrieval of Information on Scientific Projects Database; Disease Progression; Funding; Genes; Grant; HIV; HIV Infections; HIV-1; Immune response; Immune system; Individual; Infection; Institution; Purpose; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Virus; prospective; research study; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to understand how the immune system of individuals recently infected with HIV or recently exposed to HIV responds to the virus and to compare these responses to those in individuals with chronic infection. This study will also examine whether host genes (DNA) affect immune response to HIV and/or are associated with protection from HIV infection or HIV disease progression if infected.

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究的目的是了解最近感染艾滋病毒或最近暴露于艾滋病毒的个体的免疫系统如何对病毒作出反应，并将这些反应与慢性感染者的反应进行比较。 这项研究还将检查宿主基因（DNA）是否影响对HIV的免疫反应和/或与保护免受HIV感染或HIV疾病进展（如果感染）相关。