课题基金 / 基金详情

IN VIVO PET IMAGING OF VOLATILE ANESTHETIC ACTION 5HT2A RECEPTOR IN HUMAN BRAIN

IN VIVO PET IMAGING OF VOLATILE ANESTHETIC ACTION 5HT2A RECEPTOR IN HUMAN BRAIN
人脑中挥发性麻醉作用 5HT2A 受体的体内 PET 成像
批准号：
6219234
负责人：
LEONARD FIRESTONE
金额：
$0.3万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6219234
关键词：
anesthetics bioimaging /biomedical imaging clinical research human subject isoflurane positron emission tomography radiotracer serotonin receptor

项目摘要

项目成果

LEONARD FIRESTONE的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The mechanisms of volatile general anesthetics remain unclear. One of the putative targets for volatile general anesthetics is the brain serotonin receptor. This study will test the hypothesis that the 5HT2A receptor will not show a conformational change from anesthesia. The binding of the radiotracer 18F-altan-serin will be measured by PET in the presence of an anesthetizing concentration of isoflurane to that in isoflurane's absence will be compared.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DO VOLATILE ANESTHETICS MODULATE BENZODIAZEPINE BINDING TO CEREBRAL NEURONS
DO VOLATILE ANESTHETICS MODULATE BENZODIAZEPINE BINDING TO CEREBRAL NEURONS
IN VIVO PET IMAGING OF VOLATILE ANESTHETIC ACTION 5HT2A RECEPTOR IN HUMAN BRAIN
IN VIVO IMAGING OF VOLATILE ANESTHETIC ACTION 5HT2A RECEPTOR IN HUMAN BRAIN