CALM-PD PARALLEL GROUP DP, STUDY OF PRAMIPEXOLE AND CARBIDOPA-L IN PD

CALM-PD 平行组 DP，普拉克索和卡比多巴-L 在 PD 中的研究

• 批准号: 6303842
• 负责人: ROGER M KURLAN
• 金额: $ 1.48万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2001-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6303842
• 关键词: Parkinson's disease; antiparkinson drugs; clinical research; dopamine agonists; human subject; human therapy evaluation; mental disorder chemotherapy; nervous system disorder chemotherapy

The primary goal of this study is to compare the initial treatment with pramipexole and initial treatment with carbidopa-levodopa in early, symptomatic PD with regard to the development of dopaminergic motor complications. Dopaminergic motor complications are defined as: wearing-off, on-off effects, and dyskinesias.

本研究的主要目的是比较普拉克索初始治疗和卡比多巴-左旋多巴初始治疗早期症状性PD患者多巴胺能运动并发症的发生情况。多巴胺能运动并发症定义为：磨损、开关效应和运动障碍。