Parkinson's Disease Data Organizing Center

描述(申请人提供)：为响应RFA-NS-NS-05-001，我们建议在罗切斯特大学建立帕金森氏病数据组织中心(PD-DOC)。为了与RFA保持一致，PD-DOC将：1)建立、维护和传播一个共享的、中央的和标准化的纵向数据库，以支持对PD患者和对照的临床、神经病理和生物数据的前瞻性收集和分析；2)评估并朝着潜在的整合先前存在的相关数据库的方向发展；3)协助计划使用共享数据库进行研究的研究人员；4)准备和维护可能用于PD研究的参与地点的最新研究材料目录；5)协调PD-DOC指导委员会的年度会议。罗切斯特大学拥有广泛的专业知识和资源，这将促进非常成功的PD-DOC的发展。PD-DOC将成为推动PD合作研究的关键力量。

DESCRIPTION (provided by applicant): In response to RFA-NS-NS-05-001, we propose to establish a Parkinson's Disease Data Organizing Center (PD-DOC) at the University of Rochester. In keeping with the RFA, the PD-DOC will: 1) establish, maintain and disseminate a shared, central and standardized longitudinal database in support of the prospective collection and analysis of clinical, neuropathological and biologic data from patients with PD and controls, 2) assess and move toward the potential integration of relevant pre-existing databases, 3) assist investigators planning to perform research studies using the shared database, 4) prepare and maintain an up-to-date catalog of research materials at participating sites that might be used for PD research and, 5) coordinate annual meetings of the PD-DOC Steering Committee. The University of Rochester has extensive expertise and resources which will facilitate the development of a highly successful PD-DOC. The PD-DOC will be a critical force in advancing collaborative research in PD.