HIV VACCINE PREPAREDNESS STUDY AND EFFICACY TRIAL

HIV 疫苗准备研究和功效试验

• 批准号: 6305960
• 负责人: MICHAEL MARMOR
• 金额: $ 2.1万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6305960
• 关键词: AIDS vaccines; HIV infections; clinical research; clinical trials; epidemiology; genetic polymorphism; health behavior; human immunodeficiency virus; human subject

This proposal is for HIV Vaccine Preparedness studies with the following aims: 1) assess the feasibility of a vaccine efficacy trial in NYC. 2) to determine the seroincidence of HIV and its association with behavioral and biological cofactors; 3) to validate risk assessment scales to measure risk behavior associated with HIV transmission: 4) to evaluate the antigenic and genetic variability of HIV in the study population; 5) to contribute specimens for subsequent genetic and immunologic analysis.The lab was used for the following: DNA isolation, blood separation and use of laminar flow hoods.

本提案是关于HIV疫苗准备研究的，目的如下：1）评估在纽约市进行疫苗有效性试验的可行性。2)确定HIV的血清发病率及其与行为和生物学辅助因子的关系; 3）验证风险评估量表，以测量与HIV传播相关的风险行为; 4）评估研究人群中HIV的抗原和遗传变异性; 5）为随后的遗传和免疫学分析提供标本。DNA分离、血液分离和层流罩的使用。