CORE--CLINICAL FACILITY

艾滋病研究中心的临床支持核心提供各种服务，鼓励纽约大学艾滋病研究中心迅速开展以患者为基础的研究。提供的服务包括：(1)流行病学和生物统计学咨询；(2)生物数学建模；(3)处理和储存来自艾滋病毒感染者和未感染对照的生物样本；(4)对储存在CFAR临床支持中心或CFAR调查员实验室的样本进行编目和分发；以及(5)采购用于艾滋病毒/艾滋病研究的新鲜生物样本。本清单中的服务“2”和“5”是核心活动的新成员或新成员。在生物统计学、生物数学和流行病学领域，核心对协助设计和分析研究、或创建或应用数学模型的请求作出回应，并积极开展外联活动，寻求将核心的专门知识应用于CFAR组成研究方案的方法。与CFAR中每个主要实验室的联络被分配到一个特定的核心中心，专业样本管理活动与流行病学咨询紧密结合，即鼓励希望将样本存储在临床支持核心设施中的调查人员以标准化形式提交数据，描述来源患者的艾滋病毒风险、人口统计和临床特征。希望获得特定类型患者标本的调查人员被转介给已存储适当标本或在Core中招募适当患者的同事。除了标本和管理服务外，临床支持中心还提供流行病学和生物统计咨询，确保避免不必要地重复收集患者的生物样本。

The Clinical Support Core of the Center for AIDS Research provides a variety of services to encourage the rapid conduct of patient-based research at the NYU CFAR. The services provided are: (1) epidemiological and biostatistical consultation; (2) biomathematical modeling; (3) processing and storage of biological samples from HIV- infected patients and uninfected controls; (4) cataloguing and distribution of information on specimens stored either in the CFAR Clinical Support Core facilities or in the laboratories of CFAR investigators; and (5) procurement of fresh biological samples for HIV/AIDS studies. Services "2" and "5" in this list are recent or new addition to the Core's activities. In the areas of biostatistics, biomathematics and epidemiology, the Core responds to requests for assistance in the design and analysis of studies, or for the creation or application of mathematical models, and also engages in active outreach to seek ways in which the Core's expertise can be applied to CFAR's constituent research programs. Liaison with each of the major laboratories in the CFAR is assigned to a specific Core professional Specimen management activities are closely integrated with epidemiological consultation, i.e., investigators wishing to store specimens in the Clinical Support Core facilities are encouraged to submit data on a standardized form describing the HIV-risk, demographic, and clinical characteristics of source patients. Investigators wishing access to specific types of specimens of patients than are referred to colleagues who have stored appropriate specimens or enrolled appropriate patients with the Core. The Clinical Support Core's provision of epidemiological and biostatistical consultation in addition to specimen and management services ensures that unnecessarily duplicative collection of biological samples from patients is avoided.