A HAND-HELD CONFOCAL SCANNING OPHTHALMOSCOPE

手持式共焦扫描检眼镜

• 批准号: 6384728
• 负责人: JIM HANG
• 金额: $ 41.12万
• 依托单位: NEW DIMENSION RESEARCH & INSTRUMENT
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2002-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6384728
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; clinical biomedical equipment; confocal scanning microscopy; diagnosis design /evaluation; digital imaging; eye disorder diagnosis; eye fundus photography; image processing; laboratory rabbit; lasers; ophthalmoscopy; portable biomedical equipment; rapid diagnosis; telemedicine; vision tests

In this Phase II we propose to develop a low cost, hand-held, non- mydriatic ophthalmoscope. Since there are no compact or rugged non- mydriatic ophthalmpscopes for field use, the diagnosis and treatment of eye injuries require trained specialists at remote locations from emergency rooms or primary care facilities. The resulting delays in diagnosis and treatment for soldiers and civilians cause increases in visual disability. Our innovative ophthalmoscope will provide the much needed timely diagnosis of eye diseases and trauma. This novel ophthalmoscope also has the capability to administer basic visual function tests. it incorporates an addressable laser/detector array chip, a digital image processor, and a liquid crystal display in one system. Unlike conventional ophthalmoscopes, our device has NO moving parts or bulky optics. it may be either integrated with a digital camera or connected to a laptop computer. Results from Phase I efforts have demonstrated the feasibility of using the laser/detector array and bilens for confocal imaging. The objective of Phase II is to demonstrate confocal imaging of retina with a 256x256 laser/detector array. We will deliver a functional prototype at the end of this Phase II. PROPOSED COMMERCIAL APPLICATION: Once fully developed, the proposed ophthalmoscope will allow providers at forward medical facilities to image fundus of injured soldiers and civilians, and send the images to specialists at distant sites. The providers on the scene will be able to receive diagnostic interpretations and treatment recommendations from experts without delay.

在第二阶段，我们建议开发一种低成本、手持式、无散瞳的检眼镜。由于没有紧凑型或坚固型的非散瞳检眼镜供现场使用，眼部损伤的诊断和治疗需要在急诊室或初级保健设施的偏远地区训练有素的专家。由此造成的对士兵和平民的诊断和治疗延误导致视力残疾的增加。我们创新的检眼镜将为眼科疾病和创伤提供急需的及时诊断。这种新型检眼镜还具有进行基本视觉功能测试的能力。它在一个系统中集成了一个可寻址激光/探测器阵列芯片、一个数字图像处理器和一个液晶显示器。与传统的检眼镜不同，我们的设备没有活动部件或笨重的光学元件。它可以与数码相机集成，也可以连接到笔记本电脑上。第一阶段的结果已经证明了使用激光/探测器阵列和双透镜进行共聚焦成像的可行性。第二阶段的目标是用256x256激光/探测器阵列演示视网膜的共聚焦成像。我们将在第二阶段结束时交付一个功能原型。拟议的商业应用：一旦完全开发，拟议的检眼镜将允许前沿医疗设施的提供者对受伤士兵和平民的眼底进行成像，并将图像发送给遥远地点的专家。现场的医疗服务提供者将能够及时收到专家的诊断解释和治疗建议。