NYS FAMILY STUDY: PROBLEM ALCOHOL USE & PROBLEM BEHAVIOR

描述（申请人摘要）：本申请是一个主要的 问题酒精使用及相关问题代际和生命过程研究 问题行为，包括受害和犯下暴力和 其他刑事犯罪，非法药物使用，高风险性行为，以及 心理健康问题拟议的研究涉及收集 人口、社会心理、态度、行为和生物数据 (DNA)三代受访者。中产阶级已经成为 一项主要的纵向研究，全国青年调查（NYS），首先 收集了受访者及其父母的数据（1976年，当时 受访者是11- 17岁的青少年，并继续 收集到1992年的原始答复者的数据，当时答复者是 27-33岁。拟议中的研究包括重新采访 原受访者及其父母，并采访了配偶和 第一次是最初的受访者的孩子。也是第一 当时，我们会从最初的受访者，配偶， 孩子，父母，以及其他生物相关的个体。这些数据， 结合双胞胎研究（CATS）和收养研究的平行数据， (CAP)将提供一个独特的强大的设计分析， 酗酒和其他问题代际传递 行为。研究的具体目标是：（1）描述和分析 问题酒精使用的代际异同， 相关的行为，社会心理和态度特征， 11-17岁受访者的全国家庭概率抽样 1999-2000年，他们的子女（1989年以前）， 分析问题酒精使用的传播途径 和其他问题行为从父母到孩子使用社会人口统计学， 来自全国家庭的社会心理、态度和遗传数据 概率样本，采用样本和双胞胎样本;（3）分析 从生命过程发展的角度来看问题酒精使用，包括 生命历程中的个体内变化和个体间差异 青少年问题酒精使用的成年后果;（4）延长 11-33岁全国抽样流行病学数据的覆盖范围 包括34-40岁。

DESCRIPTION (Applicant's abstract): This application is for a major intergenerational and life course study of problem alcohol use and related problem behavior including the victimization and perpetration of violent and other criminal offenses, illicit substance use, high-risk sexual behavior, and mental health problems. The proposed research involves collection of demographic, social psychological, attitudinal, behavioral, and biological data (DNA) on three generations of respondents. The middle generation has been part of a major longitudinal study, the National Youth Survey (NYS), which first collected data on the respondents and (their parents in 1976, when the respondents were adolescents 11-1 7 years old, and which has continued to collect data on the original respondents through 1992, when respondents were 27-33 years old. The proposed research involves re- interviewing both the original respondents and their parents, and also interviewing the spouses and children of the original respondents for the first time. Also for the first time, we would collect DNA samples from the original respondents, the spouses, children, and parents, and other biologically relevant individuals. These data, combined with parallel data from a twin study (CATS) and an adoption study (CAP) would provide a uniquely powerful design for the analysis of intergenerational transmission of problem alcohol use and other problem behaviors. Specific objectives for the research are (1) to describe and analyze intergenerational similarities and differences in problem alcohol use and related behavioral, social psychological, and attitudinal characteristics of a national household probability sample of respondents who were 11-17 years old in 1976 and their children (from before 1989) in 1999-2000, at the same age for parents and children; (2) to analyze the transmission of problem alcohol use and other problem behaviors from parents to children using socio-demographic, social psychological, attitudinal, and genetic data from a national household probability sample, an adoption sample, and a twin sample; (3) to analyze problem alcohol use in a life-course developmental perspective, including both intra-individual change over the life course and inter-individual differences in the adult consequences of adolescent problem alcohol use; and (4) to extend the coverage of the epidemiological data on the national sample from ages 11-33 to include ages 34-40.