A novel mechanism for IL-1β secretion

IL-1β 分泌的新机制

• 批准号: nhmrc : GNT1122240
• 负责人: A/Pr Kate Schroder
• 金额: $ 60.82万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-mechanism-il-1-secretion/1347260
• 关键词: novel; mechanism; IL; secretion

During injury or infection, our body’s immune system protects us by launching inflammation. But uncontrolled inflammation drives common diseases such as cancer, diabetes and Alzheimer’s. This project will reveal how the body produces interleukin-1β – a protein at the heart of inflammation and disease – so we can design better strategies for treating patients with inflammation-driven disease.

在受伤或感染期间，我们身体的免疫系统通过产生炎症来保护我们。但不受控制的炎症会引发癌症、糖尿病和阿尔茨海默氏症等常见疾病。这个项目将揭示人体如何产生白细胞介素-1β -一种炎症和疾病的核心蛋白质-所以我们可以设计更好的策略来治疗炎症驱动疾病的患者。