Inhibitors of NLRP3 activation for treatment of inflammatory CNS diseases

NLRP3 激活抑制剂用于治疗炎症性中枢神经系统疾病

• 批准号: nhmrc : 1086786
• 负责人: A/Pr Kate Schroder
• 金额: $ 68.22万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/inhibitors-nlrp3-activation-cns-diseases/519146
• 关键词: Inhibitors; NLRP3; activation; treatment; inflammatory

This project will use novel tool compounds to advance our understanding of inflammatory brain diseases such as Parkinson's disease and Multiple Sclerosis. We will examine the molecular pathways and identify novel means to treat these debilitating diseases. We will then aim to design novel therapeutics which target these pathways.

该项目将使用新的工具化合物来促进我们对帕金森病和多发性硬化症等炎症性脑疾病的理解。我们将研究分子途径，并确定治疗这些衰弱性疾病的新方法。然后，我们将致力于设计针对这些途径的新疗法。