Caspase 8 apoptotic signalling induced by the inflammasome

我们身体细胞的死亡可以是一个积极和有目的的过程。程序性死亡发生在对感染的反应或对癌症变化的防御中。如果病毒感染的细胞可以在病毒复制之前死亡，这将控制感染。我们已经研究了细胞死亡对细胞质中发现的DNA的反应，这可能是感染的迹象。我们正在描述的新的细胞死亡途径与抵抗感染和肿瘤有关。

The death of cells of our body can be an active and purposeful process. Programmed death occurs in response to infection or as a defence against cancerous changes. If a virally infected cell can die prior to replication of the virus, this will control the infection. We have investigated cell death in response to DNA found in the cytoplasm of cells, which can be an indication of infection. The novel cell death pathway we are characterising is relevant to defence against infection and tumours.