A novel reproductive tract factor that protects against chlamydia

一种预防衣原体的新型生殖道因子

• 批准号: nhmrc : 1003591
• 负责人: Prof Paul Hertzog
• 金额: $ 36.08万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-reproductive-tract-protects-chlamydia/108949
• 关键词: novel; reproductive; tract; factor; protects

Chlamydia is a common cause of sexually transmitted diseases resulting in pelvic inflammatory disease, infertility and ectopic pregnancy. There are no vaccines that prevent infection or disease. We have discovered a new factor in the immune system (interferon-epsilon) that only occurs in the reproductive tract. If this factor is absent then Chlamydia infections are more severe. We will investigate how this factor protects against infection and if we can use it as a new agent against Chlamydia STDs.

衣原体是性传播疾病的常见原因，导致盆腔炎、不孕不育和异位妊娠。目前还没有预防感染或疾病的疫苗。我们已经发现了免疫系统中的一种新因子(干扰素-epsilon)，它只出现在生殖道中。如果没有这个因素，那么衣原体感染就更严重。我们将研究这种因子是如何预防感染的，以及是否可以将其用作预防衣原体性病的新制剂。