New Mechanisms of immunomodulation by interferon transsignaling

干扰素转信号免疫调节的新机制

• 批准号: nhmrc : 491172
• 负责人: Prof Paul Hertzog
• 金额: $ 36.04万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/new-mechanisms-immunomodulation-interferon-transsignaling/95634
• 关键词: New; Mechanisms; immunomodulation; interferon; transsignaling

The aim of this project is to characterise a new discovery of how the body can regulate its response to disease such as infections and cancer. Interferons are produced by the body to stimulate immune reactions to these diseases. We have dicovered that a circulating form of an interferon binding protein or receptor can change the nature of an immune response. We plan to study how this is achieved and whether this information can be used therapeutically.

该项目的目的是描述身体如何调节其对感染和癌症等疾病的反应的新发现。人体产生干扰素是为了刺激对这些疾病的免疫反应。我们发现一种循环形式的干扰素结合蛋白或受体可以改变免疫反应的性质。我们计划研究这是如何实现的，以及这些信息是否可以用于治疗。