TYPHOON 8600 VARIABLE MODE IMAGER

描述：（调查员？s摘要）：所要求的仪器是ABI 棱镜技术涉及多色荧光，化学荧光， 化学发光和放射性同位素检测被大量用于所有 研究学科。在此应用程序中，我们要求分子 Dynamics Typhoon 8600可变模式成像仪。这台最先进的成像仪 能够执行所有多色荧光，化学荧光， 化学发光和无膜放射自显影成像分析。的 仪器快速，易于使用，节省资金，无需 电影，占用最小的实验室空间，并可用于 涉及几乎任何样品成像的各种应用。我们有 在大多数人中， 马歇尔大学医学院的活跃研究人员。在 除了一组七个，联邦资助的主要用户与广泛的 研究兴趣，包括分子遗传学，毒理学，神经科学， 免疫学和细胞生物学，我们已经确定了一组未成年人用户， 潜在的外部用户，他们将从台风中受益匪浅 8600成像仪。虽然这种类型的仪器是许多研究的标准 设施，个人很难获得这种仪器 像我们这样财力有限的小机构的研究人员 资源提供具有广泛功能的共享成像仪 8600号台风将大大增强我们迅速和成功地 实现我们资助的研究项目的许多具体目标。 这反过来将促进我们机构研究人员的能力， 在为一些与人类健康有关的 这些问题是我们资助研究的长期目标。

DESCRIPTION: (Investigator?s Abstract): The instrument requested is the ABI prism Techniques involving multi-color fluorescence, chemifluorescence, chemiluminescence, and radioisotopic detection are abundantly used in all research disciplines. In this application, we are requesting a Molecular Dynamics Typhoon 8600 Variable Mode Imager. This state-of-the-art imager has the capability to perform all multi-color fluorescence, chemifluorescence, chemiluminescence, and filmless autoradiography imaging analyses. The instrumentation is quick, easy to use, saves money by eliminating the need for film, takes up a minimal amount of laboratory space, and can be used for a wide-variety of applications involving imaging of almost any sample. We have identified a tremendous need for this type of instrumentation among a majority of the active researchers at the Marshall University School of Medicine. In addition to a group of seven, federally funded major users with a wide-range of research interests, including molecular genetics, toxicology, neuroscience, immunology, and cell biology, we have identified a group of minor users and potential outside users who would greatly benefit from access to the Typhoon 8600 imager. While this type of instrumentation is standard at many research facilities, acquisition of such instrumentation is difficult by individual researchers at a small institution such as ours with limited financial resources. Availability of a shared imager with the wide capabilities of the Typhoon 8600 would greatly enhance our ability to quickly and successfully accomplish many of the specific objectives of our funded research projects. This, in turn, will facilitate the ability of researchers from our institution in contributing important knowledge toward a number of human health-related issues that are long-term goals of our grant-funded research.