CENTER ON SOCIAL INEQUALITIES, MIND & BODY

总体描述：密歇根社会不平等、心理和身体跨学科中心将培养一个跨学科培训项目，旨在了解心理状态、它们的决定因素、压力和压力的病理生理标志在儿童发育和衰老中身心障碍发展中的相互作用。该中心将重点关注健康方面的社会经济和种族不平等，以及以人口为基础的儿童和成人、男子和妇女、白人和少数民族样本的生命历程和社区决定因素。建议的项目将集中于：(1)儿童的情绪、身体和认知状况在多大程度上反映了父母社会经济地位、收入轨迹、经济压力和社区特征的影响；(2)糖皮质激素和血清素机制在社会心理状态、社会经济地位和心血管疾病风险之间的关联中的作用；(3)在多层次代表性社区样本中，广泛的心理属性与压力的相关生物标志物之间的相互关系。(4)研究生命不同阶段的社会经济、生物和心理社会因素对心理健康、心血管风险因素状况等广泛指标的贡献；(5)随机选择的贫困妇女队列的慢性经济压力对健康和功能的影响。该中心还将强调发展新的方法和生物统计工具，职业发展的新途径，并将强调向政策对象传播研究结果。该中心将涉及来自9个学科的22名高级研究人员的合作。

OVERALL DESCRIPTION: The Michigan Interdisciplinary Center on Social Inequalities, Mind and Body will foster an interdisciplinary training program seeking to understand the interactions of psychological states, their determinants, stress and pathophysiologic markers of stress in the development of physical and mental disorders in child development and in aging. The center will focus on socioeconomic and racial inequalities in health, and on lifecourse and community determinants in population-based samples of children and adults, men and women, whites and minorities. The proposed projects will focus on: (1) the extent to which children's emotional, physical and cognitive status reflect the influence of parental socioeconomic status, income trajectories, economic stress and community characteristics, (2) the role of glucocorticoid and seratonergic mechanisms in the association between psychosocial states, SES and risk for CVD, (3) the interrelations between a broad array of psychological attributes and related biological markers of stress within a multilevel representative community sample, (4) a study of the contributions of socioeconomic, biological and psychosocial factors at different stages of the lifecourse to a broad range of indicators of psychological wellbeing, cardiovascular risk factor status and (5) the impact of chronic economic stress on health and function in a randomly selected cohort of poor women. The Center will also emphasize the development of new methodological and biostatistical tools, novel approaches to career development and will emphasize the dissemination of research findings to policy audiences. The Center will involve the collaboration of 22 senior researchers from nine disciplines.