A prospective, open-label, single-centre/multi-site, randomized clinical trial of a novel maternal microbiological “screen & treat” program compared with normal care for the prevention of preterm birth

点击翻译按钮获取中文摘要

In 2014, our team launched the world-unique Western Australian Preterm Birth (PTB) Prevention Initiative and reduced the rate of PTB state-wide by 8%. Our next step is to trial a “screen & treat” program to detect women in mid-pregnancy at high risk of infection-driven PTB and treat them with antimicrobial medications. The study will involve more than 6000 women and aims to lower the rate of spontaneous PTB rate by 30%, which if applied nationally, may prevent 4500 PTBs each year.