CINGULATE CORTEX IN SELECTIVE ATTENTION--FMRI STUDY

拟议工作的目的是为了更好地了解 前扣带回在选择性脑缺血中的特殊作用(S) 请注意。特别令人感兴趣的是确定阶段 行政协调会参与调解冲突的程序 解决方案(Gehring，1993)和所需的冲突程度 它的活动。拟议的实验将利用 Stroop任务，因为此任务提供了对选择性 请注意。功能磁共振将用于检测特定于任务的变化 在反腐败委员会的活动中。 第一个实验将确定ACC活动是否 与反应干扰有关。这将通过以下方式实现 确定其在Stroop任务中的活动是否依赖于 或者不是这个不一致的词命名为合格的回答。第二 实验将确定ACC的活动是否依赖于 存在语义冲突的AS程度。要做到这一点，接入增加 在干扰条件下的活动将被检查为a函数 不一致的词的相对语义值。第三 实验将确定ACC的活动是否依赖于 反应阶段的冲突程度。要做到这一点，接入增加 在干扰条件下的活动将被视为 刺激的相对强度对反应映射的作用 与不一致的单词相关联。 更具体地了解行政协调会在以下方面的作用 最近，选择性注意对医学领域具有重要意义 神经成像研究已将ACC功能障碍与注意力缺陷联系起来 在临床人群中观察到的个体患有 精神分裂症或注意力缺陷多动障碍。

The purpose of the proposed work is to provide a better understanding of the specific role(s) of anterior cingulate cortex (ACC) in selective attention. Of particular interest is the determination of the stages of processing at which the ACC is involved in mediation of conflict resolution (Gehring, 1993) and the degree of conflict required to invoke its activity. The proposed experiments will make use of variants of the Stroop task, as this task provides for direct manipulation of selective attention. Functional MRI will be used to detect task specific changes in the ACC's activity. The first experiment will establish whether or not ACC activity is linked to response interference. This will be accomplished by determining if its activity in the Stroop task is dependent on whether or not the incongruent word names an eligible response. The second experiment will determine if the ACC's activity is dependent on the degree of as semantic conflict present. To do so, increases in ACC activity during the interference condition will be examined a a function of the relative semantic value of the incongruent word. The third experiment will determine if the ACC's activity is dependent on the degree of conflict at the response stage. To do so, increases in ACC activity during the interference condition will be examined as a function of the relative strength of the stimulus to response mappings associated with the incongruent word. The development of a more specific understanding of the ACC's role in selective attention is of importance to the medical field, as recent neuroimaging studies have linked ACC dysfunction to attention deficits observed in clinical populations such as individual suffering from schizophrenia or attention-deficit-hyperactivity-disorder.