PREDICTORS OF HEALTH AND LONGEVITY

健康和长寿的预测因素

• 批准号: 6349721
• 负责人: HOWARD S. FRIEDMAN
• 金额: $ 20.02万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-01 至 2005-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6349721
• 关键词: aging; behavioral /social science research tag; child psychology; clinical research; cognition; coping; disease /disorder etiology; divorce /separation; exercise; gender difference; health behavior; human data; human mortality; human old age (65+); longevity; longitudinal human study; marriage /marital status; mental health epidemiology; personality; psychological stressor; quality of life; religion; social psychology; social support network; substance abuse related disorder

This competing continuation project will employ the 7-decade longitudinal Terman data to examine relationships between theoretically key behavioral and psychosocial predictors and longevity/cause of death/healthy aging. This interdisciplinary research will test hypothesized relations involving the mechanisms of physical activity patterns, risk- taking, religiosity and contentment, changes in social integration across time, explanatory style and resilience, gender diagnostics, substance use, and facets of personality as they predict health many years later. The design is an archival prospective cohort study, using statistical survival analyses and related regression analyses. Because of the long-term nature and richness of the data, this project can compare competing models, can examine long-term effects and time-related changes, and can compare major causes of death. This is consistent with calls for intensive studies of individual differences in behavior patterns, health and disease. Much of the raw data come from the archive begun in 1921 by L. Terman, plus extensive additional data already collected by this project on date of death, cause of death, smoking, and various indexes of personality and social stability. The subjects are 856 men and 672 women followed from their childhood in the 1920's until the present, the longest continuous cohort study every conducted. Following up on the ongoing research, which uncovered links between major psychosocial patterns earlier in life and subsequent premature death in middle and old age, the present project will employ reliable behavioral patterns and psychosocial indices to compare models containing these and related later-life psychosocial stresses and resources. This project thus aims to provide hard-to-obtain information relevant to understanding the influence of these social, individual, and behavioral factors on longevity and cause of death across the life span.

这个竞争的延续项目将采用70年的纵向特曼数据来检查理论上关键的行为和心理社会预测因素与寿命/死亡原因/健康老龄化之间的关系。这项跨学科研究将测试假设的关系，包括身体活动模式、冒险、宗教信仰和满足感、社会融合的变化、解释风格和弹性、性别诊断、物质使用和人格方面的机制，因为它们预测了多年后的健康状况。本研究采用档案前瞻性队列研究，采用统计生存分析和相关回归分析。由于数据的长期性和丰富性，这个项目可以比较相互竞争的模型，可以检查长期影响和与时间有关的变化，并可以比较主要的死亡原因。这与对行为模式、健康和疾病方面的个体差异进行深入研究的呼吁是一致的。许多原始数据来自L. Terman于1921年开始的档案，加上这个项目已经收集的大量额外数据，包括死亡日期、死亡原因、吸烟情况以及各种个性和社会稳定性指标。研究对象是856名男性和672名女性，他们从20世纪20年代的童年一直被跟踪到现在，这是迄今为止进行的最长的连续队列研究。正在进行的研究揭示了生命早期主要的社会心理模式与随后中老年过早死亡之间的联系，在此基础上，本项目将采用可靠的行为模式和社会心理指数来比较包含这些模式和相关的晚年社会心理压力和资源的模型。因此，该项目旨在提供难以获得的相关信息，以了解这些社会、个人和行为因素对寿命和整个生命周期内死亡原因的影响。