PREDICTORS OF HEALTH AND LONGEVITY

健康和长寿的预测因素

• 批准号: 6497173
• 负责人: HOWARD S. FRIEDMAN
• 金额: $ 20.49万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-01 至 2005-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6497173
• 关键词: aging; behavioral /social science research tag; child psychology; clinical research; cognition; coping; disease /disorder etiology; divorce /separation; exercise; gender difference; health behavior; human data; human mortality; human old age (65+); longevity; longitudinal human study; marriage /marital status; mental health epidemiology; personality; psychological stressor; quality of life; religion; social psychology; social support network; substance abuse related disorder

This competing continuation project will employ the 7-decade longitudinal Terman data to examine relationships between theoretically key behavioral and psychosocial predictors and longevity/cause of death/healthy aging. This interdisciplinary research will test hypothesized relations involving the mechanisms of physical activity patterns, risk- taking, religiosity and contentment, changes in social integration across time, explanatory style and resilience, gender diagnostics, substance use, and facets of personality as they predict health many years later. The design is an archival prospective cohort study, using statistical survival analyses and related regression analyses. Because of the long-term nature and richness of the data, this project can compare competing models, can examine long-term effects and time-related changes, and can compare major causes of death. This is consistent with calls for intensive studies of individual differences in behavior patterns, health and disease. Much of the raw data come from the archive begun in 1921 by L. Terman, plus extensive additional data already collected by this project on date of death, cause of death, smoking, and various indexes of personality and social stability. The subjects are 856 men and 672 women followed from their childhood in the 1920's until the present, the longest continuous cohort study every conducted. Following up on the ongoing research, which uncovered links between major psychosocial patterns earlier in life and subsequent premature death in middle and old age, the present project will employ reliable behavioral patterns and psychosocial indices to compare models containing these and related later-life psychosocial stresses and resources. This project thus aims to provide hard-to-obtain information relevant to understanding the influence of these social, individual, and behavioral factors on longevity and cause of death across the life span.

这个竞争性的延续项目将使用70年的纵向Terman数据来检查理论上关键的行为和心理社会预测因素与寿命/死亡原因/健康老龄化之间的关系。这项跨学科的研究将测试假设的关系，涉及身体活动模式、冒险、宗教和满足感、社会融合随时间的变化、解释风格和韧性、性别诊断、药物使用以及预测多年后健康的人格方面的机制。该设计是一项档案前瞻性队列研究，使用统计生存分析和相关回归分析。由于数据的长期性和丰富性，该项目可以比较相互竞争的模型，可以检查长期影响和与时间相关的变化，可以比较主要死亡原因。这与对行为模式、健康和疾病的个体差异进行深入研究的呼吁是一致的。许多原始数据来自L.Terman于1921年开始的档案，加上这个项目已经收集的关于死亡日期、死因、吸烟以及各种人格和社会稳定指数的大量额外数据。受试者是856名男性和672名女性，他们从20世纪20年代S的童年一直跟踪到现在，这是历来进行的持续时间最长的队列研究。根据正在进行的研究，揭示了早年的主要心理社会模式与随后的中老年过早死亡之间的联系，本项目将使用可靠的行为模式和心理社会指数来比较包含这些和相关的晚年心理社会压力和资源的模型。因此，该项目旨在提供难以获得的相关信息，以了解这些社会、个人和行为因素对寿命和整个生命周期中的死亡原因的影响。