PREDICTORS OF HEALTH AND LONGEVITY

健康和长寿的预测因素

• 批准号: 2050425
• 负责人: HOWARD S. FRIEDMAN
• 金额: $ 12.74万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2050425
• 关键词: alcoholic beverage consumption; behavioral medicine; child psychology; coping; early experience; emotional adjustment; epidemiology; exercise; gender difference; health behavior; human data; human middle age (35-64); human morbidity; human mortality; human old age (65+); longevity; longitudinal human study; marriage /marital status; obesity; personality; psychobiology; psychological stressor; social psychology; social support network; tobacco abuse

The research of this revised competing continuation grant will examine the relationships between longevity/cause of death and key behavioral and psychosocial predictors. In particular, this research will test hypothesized relations between major stressor patterns and response patterns earlier in life and subsequent premature death in middle and old age. The design is an archival prospective cohort study. The raw data come from the longitudinal Terman Life Cycle Study, begun in 1921 by L. Terman and continued by R. Sears and others, plus additional data on cause of death recently collected in the ongoing research. The subjects are 857 men and 671 women followed from their childhood in the 1920's until the present, the longest continuous cohort study ever conducted. In the ongoing research, reliable indices of childhood personality, childhood stress (e.g. broken families), adult health behaviors (alcohol use, smoking, body mass), actual and perceived social support, and related indices have been created or gathered, and it has been established through statistical survival analyses that some of these key variables predict longevity across the life-span. The planned research involves the explaining of cause of death and longevity--i.e. the testing of models.--employing these and related psychosocial stresses and resources. Significant questions in behavioral medicine, psychosocial epidemiology, and health psychology involving the long-term effects of conscientiousness, optimism' social ties, and health-relevant behaviors (smoking, drinking, overeating, exercise) will be addressed using survival analyses, supplemented by logistic regression analyses as appropriate. Male/female differences in longevity, including documented differences in longevity correlates of marriage, also will be examined further in an attempt to shed light on puzzling gender differences. This study will thus provide important information relevant to our understanding of the influence of social, individual, and behavioral factors on longevity and cause of death across the life span.

这项修订后的竞争性延续补助金的研究将 研究寿命/死亡原因与关键因素之间的关系， 行为和心理社会预测因素。这尤其 研究将测试主要压力源之间的假设关系， 在生命早期和随后的反应模式 中老年人过早死亡。设计是一个档案 前瞻性队列研究。原始数据来自纵向 特曼生命周期研究，开始于1921年由L。特曼继续说 由R.西尔斯和其他人，加上死亡原因的其他数据 最近在进行中的研究中发现。受试者为857人 男性和671名女性从20世纪20年代的童年开始， 这是有史以来持续时间最长的队列研究。 在正在进行的研究中，可靠的儿童性格指数， 童年压力（如破碎的家庭），成人健康行为 （酒精使用，吸烟，体重），实际和感知的社会 已创建或收集了支持和相关索引， 已经通过统计生存分析确定， 这些关键变量中的一些预测了整个生命周期的寿命。 计划中的研究包括解释死因， 寿命-即模型的测试。使用这些和相关的 心理压力和资源。重大问题 行为医学、社会心理流行病学和健康 心理学涉及的长期影响， 乐观的社会关系，和健康相关的行为（吸烟， 饮酒，暴饮暴食，运动）将使用生存 分析，辅以逻辑回归分析， 适当男女寿命差异，包括 有记录的长寿与婚姻相关的差异， 将进一步研究，试图阐明令人困惑的 性别差异。这项研究将提供重要 与我们理解的影响有关的信息 社会、个人和行为因素对寿命和原因的影响 死亡的概率。