EARLY SOCIOECONOMIC & PSYCHOSOCIAL RISK FOR OBESITY

描述（改编自申请人的描述）：本K23的目标 建议提供与儿童肥胖症有关的研究培训。的 申请人是一名学术儿科医生，曾在 自1983年以来，贫困儿童。她曾与非裔美国人，美国人， 印第安人和西班牙裔美国人。肥胖症的流行 在美国代表性不足的少数群体中， 发展中国家来自弱势背景的儿童被安置在 多种因素导致肥胖的风险增加。该提案依赖于 五个正在进行的纵向美国和国际样本具有丰富的增长， 受试者及其家庭的人口统计学和心理学数据。的 样本包括：来自密歇根州东南部的260名学龄前儿童;两个队列 (100每一个）从美国印第安人人口显示最近迅速增加 出生体重和肥胖; 150名哥斯达黎加儿童从1岁开始研究， 现在年龄为19岁; 1000名目前5岁的智利人， 4个月; 3,400名芬兰男性和女性， 疾病本项目提出的研究培训和研究计划是 与涉及这5个纵向项目的活动密切相关。这些 正在进行的研究项目将成为继续收集数据的框架， 新数据分析和比较研究。Betsy Lozoff博士， 人类生长和发展中心和儿科教授是 项目导师。一个杰出的委员会，由儿童领域的领导人组成， 营养、行为、发育、肥胖、生物统计和健康 差异将指导培训并为研究提供建议。加哈根博士 建议探讨导致这种情况的行为和心理因素， 幼儿肥胖的附加风险。同时也不能忽视 遗传学，营养和身体活动，这项工作将促进 了解贫困在儿童肥胖中的作用。的假设 儿童有可能患肥胖症， 生物和社会因素，包括贫困，父母的心理健康， 父母对儿童营养和活动的决策将是 在五个不同的高危人群中进行了深入研究。如果肥胖是 预防，关键是要了解多层次的前兆， 针对那些可以改变的因素进行干预。

DESCRIPTION (Adapted from applicant's description): The goal of this K23 proposal is to provide research training related to childhood obesity. The applicant is an academic pediatrician who has worked in settings serving children in poverty since 1983. She has worked with African American, American Indian and Hispanic American populations. The epidemic of obesity is more severe in underrepresented minority groups in the US and increasingly in some developing countries. Children from disadvantaged backgrounds are put at increased risk for obesity by a variety of factors. This proposal relies on five ongoing longitudinal US and international samples with rich growth, demographic and psychological data on the subjects and their families. The samples include: 260 preschool children from southeast Michigan; two cohorts (100 each) from an American Indian population showing recent rapid increases in birthweight and obesity; 150 Costa Rican children studied from 1 year, who are now age 19; 1000 Chileans who are currently 5 years old and studied since 4 months; and 3,400 Finnish men and women with high rates of cardiovascular disease. The research training and research plans proposed in this project are closely linked to activities involving these 5 longitudinal projects. These ongoing research projects will be the framework for continued data collection, new data analysis, and comparative study. Dr. Betsy Lozoff, Director of the Center for Human Growth and Development and Professor of Pediatrics is the project mentor. An outstanding committee composed of leaders in child nutrition, behavior, development, obesity, biostatistics and health disparities will direct the training and advise the research. Dr. Gahagan proposes to explore the behavioral and psychological factors that cause additive risk for obesity in young children. While not ignoring the importance of genetics, nutrition, and physical activity, this work will promote understanding the role of poverty in childhood obesity. The hypothesis that children are put at risk for obesity and its consequent health problems by biologic and social factors including poverty, parental mental health, and parental-decision making about childhood nutrition and activity will be examined in depth in five different populations at risk. If obesity is to be prevented, it is critical to understand the precursors on multiple levels and target those factors that are modifiable for intervention.