A randomised controlled trial to evaluate the effectiveness of zoledronate therapy in osteonecrosis of the hip.

一项随机对照试验，旨在评估唑来膦酸盐治疗髋关节骨坏死的有效性。

• 批准号: nhmrc : 632548
• 负责人: Prof David Little
• 金额: $ 35.7万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-controlled-trial-osteonecrosis-hip/77316
• 关键词: randomised; controlled; trial; evaluate; effectiveness

Osteonecrosis of the hip is an important cause of musculoskeletal disability and finding therapeuticsolutions has proven to be challenging. A wide range of surgical treatments with variable success rates ahve been proposed for the treatment. Non-surgical treatment options are limited and usually result in a poor prognosis. This novel clinical trial research will study the protective value of a bisphosphonate in patients with osteonecrosis of the hip and evaluate the cost-effectiveness.

髋部骨坏死是肌肉骨骼残疾的一个重要原因，寻找治疗方案已被证明是具有挑战性的。已经提出了多种手术治疗方法，但成功率各不相同。非手术治疗的选择有限，通常会导致不良的预后。这项新的临床试验研究将研究双膦酸类药物在髋关节骨坏死患者中的保护价值，并评估其成本效益。