EMERGENCE AND SYNCHRONOUS ACTIVITY IN NEURONAL DYNAMICS
神经元动力学中的出现和同步活动
基本信息
- 批准号:6391635
- 负责人:
- 金额:$ 9.67万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2000
- 资助国家:美国
- 起止时间:2000-09-09 至 2005-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION: (Adapted from the Investigator's Abstract)
Emergence may be defined as the appearance of qualitatively unique collective
properties in a macroscopic system that are unpredictable from knowledge of its
microscopic elements. Thus, the key to understanding emergence lies not in the
details of the microscopic elements themselves, but rather in the interactions
between them. A vast literature is built on linear analyses of synchrony in
neuronal ensembles, but recent work has revealed that nonlinear synchronous
activities are also present. The PI is a theoretical physicist with a
background in nonlinear dynamics that has been developing a thermodynamic
formalism that quantitatively describes transitions between synchronous states
in systems of coupled nonlinear elements. This Mentored Quantitative Research
Career Development Award will permit the PI to acquire training in neuroscience
and neuroscience laboratory techniques, and to use these skills to extend and
productively apply these new theoretical tools to biomedical applications.
Accordingly, the long-term career goal of the PI is to become an effective
researcher in the biomedical applications of dynamical systems theory, with
specific emphasis on neuroscience. The theme of this research plan is: Emergent
phenomena in neuronal ensemble dynamics are related to small-scale interactions
between large numbers of individual neurons or groups of neurons. These
interactions involve both linear and nonlinear states of synchronous activity,
have structure in both time and space, and are describable within a
thermodynamic formalism. Specific hypotheses to be investigated are: (1)
macroscopic phenomena in neuronal ensembles (e.g., bursting and seizing events)
are explained by synchronous activity between individual neurons; (2) emergent
phenomena require large numbers of interacting neurons; and (3) spatially
propagating waves of synchronous activity occur in neuronal ensembles. Several
specific experiments monitoring individual neuronal behavior and simultaneous
population activity during bursting and seizing are proposed to probe the
hierarchy and structure of synchronization states.
描述:(改编自研究者摘要)
涌现可以定义为性质独特的集体的出现
宏观系统中的属性是不可预测的,从知识的,
微观元素因此,理解涌现的关键不在于
微观元素本身的细节,而是在相互作用中,
他们之间大量的文献是建立在线性分析的同步,
但最近的研究表明,非线性同步
活动也在。PI是一个理论物理学家,
在非线性动力学的背景下,
定量描述同步状态之间转换的形式主义
在耦合非线性元件的系统中。这指导定量研究
职业发展奖将允许PI获得神经科学培训
和神经科学实验室技术,并利用这些技能,
有效地将这些新的理论工具应用于生物医学应用。
因此,PI的长期职业目标是成为一个有效的
动力系统理论的生物医学应用研究员,
特别强调神经科学。本研究计划的主题是:
神经元系综动力学中的现象与小尺度相互作用有关
在大量的单个神经元或神经元组之间。这些
相互作用涉及同步活动的线性和非线性状态,
在时间和空间上都有结构,并且可以在一个
热力学形式主义具体研究假设如下:(1)
神经元集合中的宏观现象(例如,爆裂和卡死事件)
由单个神经元之间的同步活动来解释;(2)涌现
现象需要大量的相互作用的神经元;(3)空间
同步活动的传播波发生在神经元集合中。几
监测单个神经元行为的特定实验,
种群在爆发和捕获过程中的活动,
同步状态的层次和结构。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
ERNEST BARRETO其他文献
ERNEST BARRETO的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('ERNEST BARRETO', 18)}}的其他基金
CRCNS: Mechanisms of wave propagation in neuronal tissue
CRCNS:神经元组织中的波传播机制
- 批准号:
7685323 - 财政年份:2006
- 资助金额:
$ 9.67万 - 项目类别:
CRCNS: Mechanisms of wave propagation in neuronal tissue
CRCNS:神经元组织中的波传播机制
- 批准号:
7215016 - 财政年份:2006
- 资助金额:
$ 9.67万 - 项目类别:
CRCNS: Mechanisms of wave propagation in neuronal tissue
CRCNS:神经元组织中的波传播机制
- 批准号:
7285563 - 财政年份:2006
- 资助金额:
$ 9.67万 - 项目类别:
EMERGENCE AND SYNCHRONOUS ACTIVITY IN NEURONAL DYNAMICS
神经元动力学中的出现和同步活动
- 批准号:
6657261 - 财政年份:2000
- 资助金额:
$ 9.67万 - 项目类别:
EMERGENCE AND SYNCHRONOUS ACTIVITY IN NEURONAL DYNAMICS
神经元动力学中的出现和同步活动
- 批准号:
6191556 - 财政年份:2000
- 资助金额:
$ 9.67万 - 项目类别:
EMERGENCE AND SYNCHRONOUS ACTIVITY IN NEURONAL DYNAMICS
神经元动力学中的出现和同步活动
- 批准号:
6528136 - 财政年份:2000
- 资助金额:
$ 9.67万 - 项目类别:
EMERGENCE AND SYNCHRONOUS ACTIVITY IN NEURONAL DYNAMICS
神经元动力学中的出现和同步活动
- 批准号:
6793340 - 财政年份:2000
- 资助金额:
$ 9.67万 - 项目类别:
相似海外基金
Enhancement of interfacial thermal transport through evanescent electric field mediated acoustic phonon transmission for efficient cooling of high power Gallium Nitride devices
通过瞬逝电场介导的声声子传输增强界面热传输,以实现高功率氮化镓器件的高效冷却
- 批准号:
2336038 - 财政年份:2024
- 资助金额:
$ 9.67万 - 项目类别:
Standard Grant
CAREER: Securing the Future of Electric Field Measurements in Space Physics
职业:确保空间物理电场测量的未来
- 批准号:
2338825 - 财政年份:2024
- 资助金额:
$ 9.67万 - 项目类别:
Continuing Grant
PFI-TT: Water disinfection using safe and sustainable copper combined with a locally enhanced electric field
PFI-TT:使用安全且可持续的铜结合局部增强电场进行水消毒
- 批准号:
2329669 - 财政年份:2024
- 资助金额:
$ 9.67万 - 项目类别:
Continuing Grant
Heat transfer to/from a droplet passing through a microchannel under an alternating electric field
在交变电场下通过微通道的液滴之间的传热
- 批准号:
23K03708 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Collaborative Research: Quantifying the Global Electric Circuit by Data Mining of Electric Field and Radar Observations from Ground Based, Airborne and Satellite Platforms
合作研究:通过地面、机载和卫星平台的电场和雷达观测数据挖掘来量化全球电路
- 批准号:
2328464 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Standard Grant
Measurement of Electron Drift Velocity in GaN under High Electric Field
高电场下GaN电子漂移速度的测量
- 批准号:
23K13362 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Development of new forward osmosis process using DC electric field and nanoparticle slurry
利用直流电场和纳米颗粒浆料开发新型正向渗透工艺
- 批准号:
23K17080 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
New area electron accelerator with high electric field and high Q by ultra-high frequency photonic assist accelerator
超高频光子辅助加速器高电场高Q值新领域电子加速器
- 批准号:
23H00123 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Tribology and characterization of additives under an electric field
电场下添加剂的摩擦学和表征
- 批准号:
2844636 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Studentship
Research on the control of photon-magnon coupling state by strong gate electric field
强栅极电场控制光子-磁振子耦合态的研究
- 批准号:
22KJ1956 - 财政年份:2023
- 资助金额:
$ 9.67万 - 项目类别:
Grant-in-Aid for JSPS Fellows