A randomised controlled trial (RCT) of azithromycin versus doxycycline for the treatment of rectal chlamydia infection in men who have sex with men.

一项阿奇霉素与多西环素治疗男男性行为直肠衣原体感染的随机对照试验 (RCT)。

• 批准号: nhmrc : 1124172
• 负责人: A/Pr Catriona Bradshaw
• 金额: $ 54.5万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-controlled-trial-sex-men/947293
• 关键词: randomised; controlled; trial; RCT; azithromycin

Rectal chlamydia is very common among gay men; it can exist for long periods without symptoms leading to ongoing transmission. Azithromycin (1 gram single dose) or 7 days doxycycline (100mg twice daily) are the two recommended treatments globally. But, there is concern about rectal chlamydia treatment with reports of up to 22% failure following azithromycin. We will conduct a randomised trial to compare these treatments for rectal chlamydia and determine which drug works better.

直肠衣原体在男同性恋者中非常常见;它可以长期存在而没有症状，导致持续传播。阿奇霉素（1克单剂量）或7天强力霉素（100毫克，每日两次）是全球推荐的两种治疗方法。但是，有报道称阿奇霉素治疗直肠衣原体失败率高达22%，这令人担忧。我们将进行一项随机试验，比较这些治疗直肠衣原体的方法，并确定哪种药物效果更好。