TRAINING GRANT IN TERATOLOGY

描述：该培训计划的目标是培养能够帮助预防先天畸形的科学家，特别是那些由我们环境中的因素通过表观遗传诱发的出生缺陷。 尝试实现这一目标所采取的方法是将先天性畸形视为发育途径的分子扰动。因此，在学术上，学生们面临着与分子生物学和分子遗传学相关的沉重课堂负担。 这种对分子生物学的教育重点贯穿于整个培训计划，包括研讨会和期刊俱乐部，特别是实验室体验。 该申请要求支持四名博士前学生和三名博士后研究员。 大多数学员将在儿童医院研究基金会工作。

DESCRIPTION: The goal of this training program is to generate scientists who can help in the fight to prevent congenital malformations, especially those birth defects induced epigenetically, by agents in our environment. The approach taken to try and reach this goal has been to view congenital malformations as molecular perturbations of developmental pathways. Thus, academically, the students encounter a heavy class load related to molecular biology and molecular genetics. This educational focus on molecular biology is carried on throughout the training program including seminar and journal clubs, and especially in laboratory experiences. The application requests support for four predoctoral students and three postdoctoral fellows. The majority of trainees will work in the Children's Hospital Research Foundation.