Gordon Research Conference on Elastin & Elastic Fibers

描述（由申请人提供）：弹性蛋白和弹性纤维戈登 研究会议将于2001年夏季举行第12次会议。这 会议是对弹性纤维感兴趣的科学家的首要会议 生物学、生物化学和病理生理学。还感兴趣的是， 结缔组织生物化学相关领域的科学家， 对心血管、肺、皮肤和骨骼生物学感兴趣的人。的 弹性蛋白和弹性纤维戈登会议是一个独特的机会，高级 来自世界各地的年轻科学家每隔一年聚集一次， 讨论最新和最前沿的研究进展。以来 从1993年及以前的Elastin Gordon会议更名为 戈登弹性蛋白和弹性纤维会议（1995年及以后） 多年来，本会议一直在从一次专门讨论一个单一问题的会议， 分子（弹性蛋白）以更广泛的会议覆盖弹性纤维结构， 生物学和病理生理学。最近的会议展示了这些发现 弹性蛋白和原纤维蛋白基因的突变是在 人类遗传性疾病主动脉瓣上狭窄和威廉姆斯综合征 (ELN)、马凡氏综合征（FBNI）和先天性挛缩性蛛网膜下腔畸形 （FBN2）。2001年的会议将重点研究基因突变是如何在 弹性纤维成分导致结缔组织病理生理学。在 另外，对弹性纤维组分功能的新认识（Emilin， 纤蛋白，潜在的TGF β结合蛋白）将基于 小鼠基因靶向实验和其他功能研究。最后， 生长因子和弹性纤维成分之间的相互作用将是一个新的 在这次会议上强调。这些令人兴奋的新领域也将讨论 在关于心血管和肺生物学的特别会议的背景下。 为了促进最精彩、最高品质的交流 科学在这一研究领域，以促进科学家之间的合作 在世界各地的各个层面，在学术界和工业界， 组织，并鼓励年轻科学家的职业生涯，基金是 要求报销会议费和应邀发言者的旅费 和其他参与者。

DESCRIPTION (provided by applicant): The Elastin and Elastic Fibers Gordon Research Conference will meet for the 12th time in summer of 2001. This Conference is the premier meeting for scientists interested in elastic fiber biology, biochemistry, and pathophysiology. It is also of interest to scientists working in related areas of connective tissue biochemistry and to those interested in cardiovascular, pulmonary, skin, and skeletal biology. The Elastin and Elastic Fibers Gordon Conference is a unique opportunity for senior and junior scientists from around the world to gather every other year and discuss the latest and most cutting edge developments in research. Since changing its name from the Elastin Gordon Conference (1993 and previous years) to the Gordon Conference on Elastin and Elastic Fibers (1995 and subsequent years), this Conference has been moving from a meeting devoted to a single molecule (elastin) to a broader meeting covering elastic fiber structure, biology, and pathophysiology. Recent Conferences have showcased the discoveries that mutations in genes for elastin and for the fibrillins are mutated in the human genetic disorders supravalvular aortic stenosis and Williams Syndrome (ELN), the Marfan syndrome (FBNI), and congenital contractural arachnodactyly (FBN2). The 2001 Conference will highlight investigations of how mutations in elastic fiber components result in connective tissue pathophysiology. In addition, new insights into the function of elastic fiber components (emilin, the fibulins, the latent TGFb binding proteins) will be discussed based upon gene targeting experiments in mice and other functional studies. Finally, interactions between growth factors and elastic fiber components will be a new emphasis at this Conference. These exciting novel areas will also be discussed within the context of special sessions on cardiovascular and pulmonary biology. In order to promote the exchange of the most exciting and highest quality science in this research area, to facilitate collaborations between scientists at all levels, in different parts of the world, and at academic and industrial organizations, and to encourage the careers of young scientists, funds are requested to reimburse Conference fees and travel expenses of invited speakers and other participants.