MICROBIAL TOXICITY OF ATRAZINE--DETOXIFICATION BY PHOTOLYSIS IN AQUATIC SYSTEMS

阿特拉津是S-三嗪家族的主要除草剂，一直以来 在过去的30年里，在北美广泛使用。根据 对美国环保局来说，阿特拉津可能是一种人类致癌物质。发现美国农业部 阿特拉津在50%的微生物检测中具有致突变性。光解 微生物降解可能是重要的降解过程 影响水环境中的阿特拉津。然而，形成了 芳香族污染物的光解诱变剂很可能发生在 含有农业营养素的水生环境，如 硝酸盐。需要检验的假设是，太阳和太阳的结合 可以开发光解和微生物降解来解毒 表层水生系统中的阿特拉津。这样做的一般方法是 该项目是将微生物生物测定与化学物质结合使用 鉴定和分析程序以确定命运和 阿特拉津及其光产物对表层水生生物的影响 系统。生态毒性测试将通过以下方法进行： 微生物活性和生物量。有利于完全和的条件 阿特拉津的快速去除将被开发，因此经济 将开发补救技术，以最大限度地减少 对人体健康的测试污染物。具体目标是：(1) 阿特拉津及其光敏产物对人体的生态毒性 自然水生环境微生物生物测定；(2) 确定季节/温度、PH值、选择的影响 增感剂、硝酸盐/亚硝酸盐浓度、 铁/亚铁盐和腐殖质的持久性和 受试化合物的毒理学特性；(3)开发 减少环境污染的经济修复技术 装载阿特拉津及其摄影产品。长期目标 是：(1)制作生态系统健康评估数据库 并提供更准确的方法来最小化 测试化合物对人体健康的影响；(2)加强 卓越的研究水平和学术表现标准 杰克逊州立大学在生物医学和环境领域 科学；(3)进一步加强合作研究 JSU与美国陆军工程兵团航道实验 密西西比州维克斯堡的车站。

Atrazine is a major herbicide of the s-triazine family which has been extensively used in North America over the last 30 years. According to the U.S. EPA, atrazine is a possible human carcinogen. USDA found atrazine mutagenic in 50% of microbial assays reviewed. Photolysis and microbial degradation may be important degradative processes affecting atrazine in aquatic environments. However, formation of mutagens by photolysis of aromatic pollutants is likely to occur in aquatic environments containing agricultural nutrients such as nitrate. The hypothesis to be tested is that a combination of sun- lit photolysis and microbial degradation can be developed to detoxify atrazine in surface aquatic systems. The general approach of this project is to use microbial bioassays in conjunction with chemical identification and analysis procedures to determine the fates and effects of atrazine and its photo products in surface aquatic systems. Testing of the ecotoxicity will be conducted with assays of microbial activities and biomass. Conditions favoring complete and fast removal of atrazine will be exploited, hence economical remediation technologies will be developed to minimize the impact of the test pollutant on human health. The specific aims are: (1) To determine the ecotoxicity of atrazine and its photo products in natural aquatic environments with microbial bioassays; (2) To determine the effect of seasons/temperature, pH, selected sensitizers, concentration of nitrate/nitrite, concentrations of ferric/ferrous salts, and humic substances of the persistence and toxicological properties of the test compounds; (3) To develop economical remediation technologies to reduce the environmental loading of atrazine and its photo products. The long-term objectives are: (1) To produce the data base of the ecosystem health assessment of atrazine and to provide more accurate methods to minimize the impact of the test compounds on human health; (2) to enhance the level of research excellence and standards of academic performance of Jackson State University in the areas of biomedical and environmental sciences; (3) to further strengthen collaborative research efforts between JSU and US Army Corps of Engineers Waterways Experiment Station at Vicksburg, Mississippi.