在线二维蛋白质组差异显示-猫眼课题宝

在线二维蛋白质组差异显示

批准号：

6338292

负责人：

Babak Esmaeli-Azad

金额：

$50.94万

依托单位：

BIOARRAY TECHNOLOGIES, INC.

依托单位国家：

美国

项目类别：

财政年份：

1999

资助国家：

美国

项目状态：

已结题

起止时间：

1999-05-10 至 2003-03-14

来源：

https://reporter.nih.gov/project-details/6338292

关键词：

SDS polyacrylamide gel electrophoresis biomedical equipment development biotechnology cadmium differential display technique digital imaging gel electrophoresis high throughput technology information display online computer protein sequence protein structure function proteomics radiation detector radionuclide imaging /scanning radionuclides tellurium zinc

中文摘要

翻译

描述（由申请人提供）：拟议研究的目标和开发是创建一个完整的实验室原型在线数字用于二维凝胶电泳多色分析的检测系统基于蛋白质组学第一阶段的可行性研究表明，原型系统，以检测和定量个别蛋白质点，因为他们通过二维SDS-聚丙烯酰胺凝胶电泳迁移。在全面发展，这个在线系统使所有的蛋白质制图在生物体、细胞或组织中的丰度水平是可能的。多色蛋白质制图允许精确的蛋白质差异显示， to generation生成of functional功能information信息about biological生物paradigms范例.这种类型为了充分了解基因的功能，和他们的产品在后基因组时代。拟定商业应用：不可用

英文摘要

DESCRIPTION (provided by applicant): The goal of the proposed research and development is to create a completed laboratory prototype online digital detection system for multi-color analysis of 2-dimensional gel electrophoresis based proteomics. Phase I feasibility studies have shown capability of this prototype system to detect and quantitate individual protein spots as they migrate through the 2nd dimension SDS-Polyacrylamide Gel Electrophoresis. In full development, this online system makes cartography of proteins of all abundance levels in an organism, cell or tissue possible. Multi-color cartography of proteins permits accurate protein differential display leading to generation of functional information about biological paradigms. This type of information is necessary for the full understanding of the function of genes and their products in the post-genome era. PROPOSED COMMERCIAL APPLICATION: Not Available

期刊论文(0)

专著(0)

科研奖励(0)

会议论文