在线二维蛋白质组差异显示-猫眼课题宝

在线二维蛋白质组差异显示

批准号：

6540629

负责人：

Babak Esmaeli-Azad

金额：

$51.3万

依托单位：

BIOARRAY TECHNOLOGIES, INC.

依托单位国家：

美国

项目类别：

财政年份：

1999

资助国家：

美国

项目状态：

已结题

起止时间：

1999-05-10 至 2005-03-14

来源：

https://reporter.nih.gov/project-details/6540629

关键词：

SDS polyacrylamide gel electrophoresis biomedical equipment development biotechnology cadmium differential display technique digital imaging gel electrophoresis high throughput technology information display online computer protein sequence protein structure function proteomics radiation detector radionuclide imaging /scanning radionuclides tellurium zinc

中文摘要

翻译

描述（由申请人提供）：提出的研究目标和

英文摘要

DESCRIPTION (provided by applicant): The goal of the proposed research and development is to create a completed laboratory prototype online digital detection system for multi-color analysis of 2-dimensional gel electrophoresis based proteomics. Phase I feasibility studies have shown capability of this prototype system to detect and quantitate individual protein spots as they migrate through the 2nd dimension SDS-Polyacrylamide Gel Electrophoresis. In full development, this online system makes cartography of proteins of all abundance levels in an organism, cell or tissue possible. Multi-color cartography of proteins permits accurate protein differential display leading to generation of functional information about biological paradigms. This type of information is necessary for the full understanding of the function of genes and their products in the post-genome era. PROPOSED COMMERCIAL APPLICATION: Not Available

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