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SSA - Life in extreme environments: adaptation and evolution of African soda lake fishes

SSA - 极端环境中的生命：非洲苏打湖鱼类的适应和进化

基本信息

批准号：
1792534
负责人：
金额：
--
依托单位：
University of York
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2016
资助国家：
英国
起止时间：
2016 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=studentship-1792534
关键词：
SSA Life extreme environments adaptation

项目摘要

How species adapt to environmental change due to continuing and accelerating pressure on the environment is important considering estimates of anthropogenic-driven climate change. Soda lake cichlids diverged from freshwater taxa a million years ago, and now live in East Africa's soda lakes Natron and Magadi, representing some of the most hostile aquatic environments known to support teleost fishes. The soda lake cichlids have adapted to survive in extreme aquatic conditions of high pH (8.8-10.2), high salinity and high temperatures (30-43 degree C). Geological evidence suggests that this adaptation may have occurred over as short a period of time as 10,000 years.This project offers the novel opportunity to identify genomic signatures of adaptation to naturally occurring extreme aquatic environments in teleost fish using sequence data from the latest high-throughput sequencing platforms. This project offers high training value combining bioinformatics and laboratory work with opportunities for fieldwork in Africa for additional sample collection.Suggested reading: Ford AGP, Dasmahapatra KK, Ruber L, Gharbi K, Cezard T, Day JJ (2015) High levels of interspecific gene flow in an endemic cichlid fish adaptive radiation from an extreme lake environment. Molecular Ecology 24: 3421-3440.This project will also be co-supervised by Dr Julia Day from the Department of Genetics, Evolution and Environment, UCL.

考虑到对气候变化的估计，物种如何适应持续和加速的环境压力造成的环境变化是很重要的。苏打湖慈鲷在一百万年前从淡水类群中分化出来，现在生活在东非的苏打湖纳特龙和马加迪，代表了一些已知的最恶劣的水生环境，以支持硬骨鱼。苏打湖慈鲷已适应在高pH值（8.8-10.2）、高盐度和高温（30-43摄氏度）的极端水生条件下生存。地质证据表明，这种适应可能发生在短短10，000年的时间内。该项目提供了一个新的机会，利用最新的高通量测序平台的序列数据来确定硬骨鱼适应自然发生的极端水生环境的基因组特征。该项目提供了很高的培训价值，将生物信息学和实验室工作与非洲实地考察的机会结合起来，以进行额外的样本收集。建议阅读：福特AGP，Dasmahapatra KK，Ruber L，Gharbi K，Cezard T，Day JJ（2015）High-levels of interspecific gene flow in an endogenous cichlid fish adaptive radiation from an extreme lake environment.第24章：一个人3421- 3440.该项目也将由来自UCL遗传学，进化与环境系的Julia Day博士共同监督。